FREE COMMUNICATION 16


15:15 - 16:45    CAPITAL SUITE 7/12

Free Communication Session 16 + Mini Lecture

New players in CKD-MBD

Chairs: Marten Taal, Derby, UK
             Pieter M. ter Wee, Amsterdam, The Netherlands

Mini lecture
Klotho is a key player in cardiovascular risk during dialysis
Denis Fouque, Lyon, France

FREE COMMUNICATIONS

SaO024
CALCIPROTEIN PARTICLE RIPENING INDUCES RUNX2-INDEPENDENT MINERALISATION OF HUMAN AORTIC VASCULAR SMOOTH MUSCLE CELLS
Edward Smith1, Tim D. Hewitson1, Kristen Kelynack1, Eric Hanssen2, Andreas Pasch3, Stephen G. Holt1, 1The Royal Melbourne Hosp, Nephrology, Melbourne, AUSTRALIA, 2Bio21 Molecular Science and Biotechnology Inst, Electron Microscopy Unit, Melbourne, AUSTRALIA, 3Univ Hosp Bern, Clinical Chemistry, Bern, SWITZERLAND.

SaO025
KLOTHO’S GENETIC VARIANTS IMPACTS ON SERUM KLOTHO AND CARDIOVASCULAR MORBIMORTALITY IN ADULT MAINTENANCE DIALYSIS PATIENTS.
Mathilde Luce1, Christophe Marçais2, Delphine Maucort-Boulch3, Jocelyne Drai2, Guillaume Jean4, Denis Fouque1, 1CH Lyon Sud, Dept Nephrology, Pierre-Benite, FRANCE, 2CH Lyon Sud, Biology Resource Center, Pierre-Benite, FRANCE, 3CH Lyon Sud, Biostatistiques Santé CNRS 5558, Pierre Benite, FRANCE, 4Nephrocare, Dept Nephrology, Ste Foy les Lyon, FRANCE.

SaO026
HIGH SERUM SCLEROSTIN CONCENTRATIONS IN HEMODIALYSIS PATIENTS ARE INVERSELY
RELATED TO ACTIVE LEAN TISSUE MASS (BUT NOT TO BONE MINERAL CONTENT)
Sylvie Dusilova-Sulkova1, Marta Kalousova2, Roman Safranek1, Jana Spickova1, Alena Reznickova1, Tomas Zima2, Ladislava Pavlikova3, Vladimir Palicka3, 1Univ Hosp Hradec Kralové, Hemodialysis Centre, Hradec Králové, CZECH REPUBLIC, 2Charles Univ and General Univ Hosp, Inst Medical Biochemistry and Lab Diagnostics, Prague, CZECH REPUBLIC, 3Univ Hosp Hradec Kralové, Inst Clinical Biochemistry and Diagnostics, Hradec Králové, CZECH REPUBLIC.

SaO027
CARDIO-PATHOLOGICAL EFFECTS OF FGF23 IN CKD ARE MEDIATED BY FGFR4
Alexander Grabner1,2, Ansel Amaral3, Saurav Singh1, Karla Schramm1, Alexis Sloan1, Dominik Kentrup2,  Stefan Reuter2, Hermann Pavenstaedt2, Giovana Seno Di Marco2, Myles Wolf3, Marcus Brand2, Christian Faul1, 1Univ Miami, Miller School Medicine, Dept Nephrology and Hypertension, Miami, FL, 2Univ Hosp Muenster, Dept Internal Medicine D, Muenster, GERMANY, 3North Western Univ Feinberg School Medicine, Div Nephrology, Chicago, IL.

SaO028
NOVEL STRIKING MISMUTATIONS ON GNAS1, FGF23 AND FGFR3 GENES IN CKD WITH SECONDARY HYPERPARATHYROIDISM (SH) AND SAGLIKER SYNDROME (SS). SS IS A COMBINATIONCOMPULSION OF BONE DISPLASIAS-HEREDITARY OSTEODYSTROPHIES AND CKD
Osman Demirhan1, Ahmet Arslan2, Yahya Sagliker3, Eylül Akbal1, Sercan Ergun2, Recep Bayraktar2, Hasan Sabit Sagliker4, Ekrem Dogan4, Ramazan Gunesacar5, Piril Sagliker Ozkaynak6, Nuray Paylar7, 1Cukurova Univ, Molecular Genetics, Adana, TURKEY, 2Gaziantep Univ, Molecular Genetics, Gaziantep, TURKEY, 3Cukurova Univ, Hypertension and Nephrology, Adana, TURKEY, 4Sutcu Imam Univesity, Internal Medicine, Kahramanmaras, TURKEY, 5Sutcu Imam Univesity, Molecular Genetics, Kahramanmaras, TURKEY, 6Baskent Univ, Internal Medicine, Adana, TURKEY, 7Sagliker Hypertension and Nephrology Unit, Hypertension, Adana, TURKEY.

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